Construction of a high-density genetic linkage map and identification of flowering-related QTL in erect milkvetch (Astragalus adsurgens)

Erect milkvetch (Astragalus adsurgens) is a perennial legume forage crop with economic and ecological value in livestock grazing and soil-erosion control in arid and semiarid areas worldwide.Genomic information and molecular tools to support breeding and research in the species are limited.The objectives of this investigation were to map its genome

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Architecture and development of olivocerebellar circuit topography

The cerebellum has a simple tri-laminar structure that is comprised of relatively few cell types.Yet, its internal micro-circuitry is anatomically, biochemically, and functionally complex.The most striking feature of cerebellar circuit complexity is its compartmentalized topography.Each cell type within the cerebellar cortex underwater treasures su

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Rituximab-Based Treatment, HCV Replication, and Hepatic Flares

Rituximab, a chimeric mouse-human monoclonal antibody directed to the CD20 antigen expressed on pre-B lymphocytes and mature lymphocytes, causes a profound B-cell depletion.Due to its peculiar characteristics, this drug has been used to treat oncohaematological diseases, B cell-related autoimmune diseases, rheumatoid arthritis, and, more recently,

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Stroke from Vasospasm due to Marijuana Use: Can Cannabis Synergistically with Other Medications Trigger Cerebral Vasospasm?

We present a case of imaging proven cerebral vasospasm causing ischemic stroke in a young crystal beaded candle holder patient chronically on buprenorphine-naloxone for heroin remission who started smoking cannabis on a daily basis.With cannabis legalization spreading across the states in the USA, it is important for physicians not only to be aware

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